Expert Videos

Module 1: Understanding Bone Health and Osteoporosis

What is osteoporosis and what causes it?
David Karpf, MD, of the Stanford University School of Medicine, explains what osteoporosis is, how it develops, and why it happens at the age it typically occurs. He also discusses how hormone changes, including at menopause for women, and natural bone turnover play a role in causing osteoporosis in both men and women.
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What are the symptoms of osteoporosis?
Osteoporosis is sometimes called a "silent disease". Dr. David Karpf of Stanford University describes how osteoporosis may not cause any symptoms until it is advanced, and notes two signs of possible osteoporosis that may show up before an osteoporotic fracture happens.
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What is the difference between osteopenia, osteoporosis and osteomalacia?
Women's health expert Dr. Risa Kagan, MD, describes osteopenia, osteoporosis, and osteomalacia, which is mineral-poor bone. In osteopenia and osteoporosis, changes in hormones and bone development cause bone weakening and eventually thin, brittle bones.
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Who is most at risk for osteoporosis and why?
Risa Kagan, MD, FACOG, of the University of California, San Francisco, discusses who is at risk for primary osteoporosis, which develops on its own, and secondary osteoporosis, which is caused by factors including medicines and other health conditions. Gender differences, lifestyle factors, certain medical conditions, and events in childhood and young adulthood can influence the development of peak bone mass and in turn, the risk of developing osteoporosis.
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What can I do to prevent osteoporosis?
Dr. Risa Kagan of the University of California, San Francisco, describes the role of calcium, vitamin D, certain medicines, and physical activity in protecting bone health and preventing osteoporosis. She also comments on the risks of medicines for osteoporosis and the benefits of supporting the whole person for optimal bone health.
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Why are women at greater risk than men for osteoporosis?
Risa Kagan, MD, an expert on women's health from the University of California, San Francisco, explains the role of the hormone estrogen in maintaining bone health, bone density, and bone strength. She describes when bone loss begins, how quickly it can progress around the menopausal transition, and what the consequences may be of losing up to 20 percent of bone mass during this period. She also discusses how bone loss may develop in men and the role of aging.
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Should men worry about osteoporosis? What are the signs in men?
David Karpf, MD, of Stanford University discusses how osteoporosis, or bone loss, can affect men. He explains the role of testosterone in fractures, how the different causes of osteoporosis in men and women can lead to different outcomes, and other medical conditions that can  make men vulnerable to losing bone mass.
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Can certain medications increase the risk of developing osteoporosis?
Dr. David Karpf of Stanford University describes how taking certain medications can increase bone loss. He discusses the role of steroids, blood thinners, ulcer medications, thyroid hormone, and medicines used in breast and prostate cancer treatment in raising the risk of osteoporosis. Dr. Karpf also touches on the osteoporosis risks of having a medical condition that causes the body to lose calcium regularly.
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Is there a cure for osteoporosis?
David Karpf, MD, explains that osteoporosis is a lifelong chronic condition that can be managed effectively. He describes osteoporosis treatments that can reduce the risk of fractures, including those that slow the rate at which the body reabsorbs bone. He also discusses how lifestyle changes to prevent falls can lower the risk of breaking a bone.
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Module 2: Screening and Diagnosing Bone Health and Osteoporosis

How is osteoporosis screened and diagnosed?
Risa Kagan, MD, a women's health expert from the University of California, San Francisco, discusses the importance of the DXA screening and FRAX risk assessment tool to find changes in bone density and make the diagnosis of osteoporosis.
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Who should be screened for osteoporosis?
Dr. Risa Kagan, an expert on osteoporosis, explains the importance of screening women over 65 and men over 70, for osteoporosis. She also talks about osteoporosis risk factors that may lead to being screened earlier.
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What is fracture risk assessment?
David Karpf, MD, of Stanford University, explains how fracture risk calculators can help determine the risk of breaking a bone due to osteoporosis. He also discusses how 10-year-risk is used to estimate the likelihood of breaking a bone.
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What is a bone scan?
Risa Kagan, MD, of the University of California, San Francisco, describes the difference between a bone scan for disease and a DXA scan to check the bones for osteoporosis. She tells us what the T score and Z score mean and how an ultrasound can be used to screen for osteoporosis.
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Why is screening and early detection for osteoporosis important?
Dr. David Karpf of Stanford University discusses the role of screening in preventing fractures and how knowing your screening-based risk is important for early treatment and avoidance of injuries that could be life-threatening, such as a hip fracture.
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Module 3: Managing and Treating Osteoporosis

What treatments are used for osteoporosis?
Osteoporosis expert David Karpf, MD, discusses the different types of treatments available for osteoporosis and their effectiveness. The two main categories of medication are antiresorptive drugs and anabolic drugs, which respectively help prevent bone from being reabsorbed by the body and promote development of new bone.
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How do antiresorptive drugs work in osteoporosis?
Dr. Risa Kagan, an expert on osteoporosis, discusses how antiresorptive drugs work on the osteoclasts, the cells that break down bone. She also describes the medications that are currently available, how long different medications keep working after the dose is given, how doctors can choose the best medication for you, and how they may adjust the dose to avoid side effects.
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How do anabolic drugs work in osteoporosis?
Women's health expert Risa Kagan, MD, discusses anabolic osteoporosis medications, including the practical advantages and side benefits of each, which patients may benefit most from them, and how they may be used with antiresorptive drugs. She also discusses the role of hormone therapy to help prevent bone loss in women.
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How does calcium and vitamin D help build healthy bones?
Stanford University osteoporosis expert Dr. David Karpf discusses how much calcium the average woman should get each day, how to get enough from the food you eat, and when a supplement is appropriate. Dr. Risa Kagan and Dr. Karpf discuss the role of vitamin D in maintaining bone health and the importance of checking vitamin D levels when treating osteoporosis.
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What are the best management strategies for a person with osteoporosis?
Women's health expert Risa Kagan, MD, and osteoporosis expert David Karpf, MD, discuss the value of vitamins and lifestyle changes in managing osteoporosis. Weight-bearing exercise is valuable for strengthening the body and improving balance. They discuss the changes in reflexes and muscle mass that accompany changes in bone density, and how these changes affect the types of falls and fractures that are likely to occur.
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What is a drug holiday when it comes to osteoporosis medication?
Dr. Risa Kagan, an expert on osteoporosis, explains that a drug holiday is a planned period of time that a patient stops taking a medication for anywhere from a few days to up to a year or more. A doctor may recommend a drug holiday to help the patient maintain sensitivity to the drug, to see how the body functions without it, or to reduce possible side effects.
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